Express Scripts
About Express Scripts is one of the largest pharmacy benefit managers (PBMs) in the United States and a wholly owned subsidiary of The Cigna Group (NYSE: CI). Founded in 1986 and headquartered at 1 Express Way in St. Louis, Missouri, Express Scripts was acquired by Cigna in December 2018 for approximately $67 billion and now operates as a core component of Cigna’s Evernorth Health Services segment. The company manages prescription drug plans for health insurers, employers, labor unions, and government health plans — processing more than 1.4 billion prescriptions annually and serving over 123.6 million pharmacy customers as of year-end 2025. Quick Facts (max 8) Founded 1986 HQ 1 Express Way, St. Louis, MO 63121 Industry Pharmacy Benefit Management